Faculty

Isabelle Coppens, PhD
Isabelle Coppens´ research focuses on hepatic factors crucial for the successful replication of Plasmodium.
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George Dimopoulos, PhD
The Dimopoulos team studies mechanisms of the mosquito´s immune system implicated in killing parasites.
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Ernesto Freire, PhD
Ernesto Freire´s laboratory is developing new strategies in which drug molecules maintain efficacy in the face of naturally existing polymorphisms and mutations associated with drug resistance.
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Marcelo Jacobs-Lorena, PhD
For transmission to occur, the malaria parasite has to complete a complex set of developmental events in its mosquito host. A major objective of the Jacobs-Lorena team is to investigate these events at the molecular level and to explore new insights to develop novel strategies to fight malaria.
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Nirbhay Kumar, PhD
A major focus in Nirbhay Kumar´s laboratory is understanding immunobiology of malaria transmission. The Kumar lab. is investigating molecular mechanisms involved in the differentiation and development of sexual stages of the parasite leading to mosquito infection and malaria transmission and developing a vaccine to malaria transmission.
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Sungano Mharakurwa, PhD
Sungano Mharakurwa joined the JHMRI in 2003 as project manager for the Malaria Institute at Macha. His primary research interest is in the molecular epidemiology of drug resistance in Plasmodium falciparum.
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Douglas Norris, PhD
Major research foci in the Douglas Norris lab are understanding mosquito population ecology, biology and genetics involved in malaria transmission and mutation-derived insecticide resistance.
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Fernando Pineda, PhD
Fernando Pineda and his team provide computational bioinformatics services to several JHMRI projects.
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Gary Posner, PhD
The Posner group focuses on the design, synthesis and antimalarial testing of new peroxides to develop drug candidates for malaria therapy.
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Sean Prigge, PhD
Dr. Prigge´s research focuses on fatty acid biosynthesis in the malaria parasite.
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Jason Rasgon, PhD
A major research focus of Jason Rasgon's laboratory is the development, evaluation and deployment of methods to spread introduced transgenes into natural vector populations. Ongoing projects include creation of methods to infect the mosquito Anopheles gambiae with the bacterial endosymbiont Wolbachia.
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Theresa Shapiro, MD, PhD
The Shapiro lab is evaluating the utility of a novel in vitro system for studying pharmacokinetic/pharmacodynamic (PK/PD) relationships for antimalarial compounds.
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Clive Shiff, PhD
Clive Shiff is coordinating the development of the Malaria Institute at Macha, the JHMRI-sponsored field site in Zambia.
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David Sullivan, MD
David Sullivan and his team are investigating the precise mechanism by which the one-nanometer-square heme crystal dimers are assembled into a larger "microcrystal" of 200 x 200 x 300 nanometers.
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Fidel Zavala, MD
Fidel Zavala´s team is studying the dual role of CD8+ T cells as anti-parasite effectors and regulators, using the Plasmodium yoelii system in mice.
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