Facility equipment can detect multimerization or aggregation of proteins, as well as the formation of macromolecular complexes. The equipment can measure the average particle size of molecules in solution and the binding constants for protein-ligand interactions or protein-protein interactions. The secondary structure content of proteins can be determined and compared with changes in structure upon interaction with a ligand. In addition, the atomic resolution three-dimensional structure of macromolecules and complexes can be determined. These capabilities support investigators studying malaria proteins as targets for drug discovery and vaccine design.
CONTACT for ITC, DLS and CD:
CONTACT for Xray: