Skip Navigation

JHMRI Logo

Johns Hopkins Malaria Research Institute

JHSPH Home

Make a Gift

Email this page

Print this page

Search

Home

Research

People

News

Contact

Links

About Malaria

 

Gene Array Core

Highlights ImageThe main function of the Gene Array Core Facility is to support JHMRI investigators who wish to apply global gene expression analysis to the study of host-parasite relationships.

Since it was established in 2002, the JHMRI Gene Array Core has met the goal of enabling and assisting the progress of public health research worldwide through gene expression, genotyping and proteomic studies in a variety of experimental models.

This Core conducts pilot experiments to generate data for grant applications, training experiments for students and, to date, has supported or participated in over 70 studies, including:

  • Study of the genetic and hormonal mechanism mediating gender differences in Plasmodium infection

  • Study of the alteration of expression in CD4 T cells following malaria infection

  • Cerebral and pulmonary expression changes after malaria infection in susceptible and resistant strains of mice

[IMAGE] A key accomplishment of the Gene Array Core was the design of an Affymetrix GeneChip¬© containing the full genomes of both Anopheles gambiae and Plasmodium falciparum. JHMRI investigators have played an integral part in establishing the utility of the chip for the worldwide malaria community.

CONTACT

Alan Scott, PhD Director
Anne Jedlicka, MS, Laboratory Manager
mriarray@jhsph.edu
443-287-5967

 

¬© 2014, Johns Hopkins University. All rights reserved.
Web policies, 615 N. Wolfe Street, Baltimore, MD 21205

Johns Hopkins Bloomberg School of Public Health

interest