Johns Hopkins Malaria Research Institute
This comparative intravital imaging study of human and rodent malaria sporozoites reveals that skin—in contrast to the liver and blood—is not a species-specific barrier for malaria parasites which suggests that testing antibodies, vaccines, and drugs can be done in vivo, using mice, making testing more accessible and less costly.
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JHMRI Professors Recognized for Teaching Excellence including:
Conor McMeniman, PhD |
Douglas Norris, PhD |
Clive Shiff, PhD |
David Sullivan, MD
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Abhai Tripathi, PhD, recently published in Science Translational Medicine research that identified two new possibilities to zero in on and further evaluate as candidate transmission-blocking vaccine antigens.
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Science publishes Professor Marcelo Jacobs-Lorena's research on clock genes and environmental cues that influence Anopheles mosquito swarming and mating.
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This new study of Aedes mosquitoes concludes that adult disease-transmitting mosquitoes acquire most of their bacteria—which can impede or enhance a mosquito’s ability to transmit human pathogens—from the water where the larvae breed.
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Matt Ippolito MD's recent contribution to a paper describes a race between the development of new malaria drugs and resistance to existing ones, outlining that WHO’s success depends on prolonging the efficacy of existing frontline drugs, which may be achieved by updating how drugs are combined or dosed.
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New PMI APPOINTMENT
Bloomberg School alum Raj Panjabi, MD, MPH ’06, has been appointed by President Joe Biden to serve as the President’s Malaria Coordinator, leading the U.S. President’s Malaria Initiative. Launched in 2005, the Initiative aims to reduce malaria-related mortality by 50% across 15 high-burden countries in sub-Saharan Africa.
Dr. Theresa Shapiro from @HopkinsMedicine explains why it could be a breakthrough for malaria.
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The World Health Organization estimates that in 2019, malaria caused 229 million new cases and 409,000 deaths.
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Bloomberg Philanthropies produced the video, The War on Malaria, telling how Johns Hopkins Malaria Research Institute Scientists lead the fight.
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With a life-long interest in global health and a shared Nobel Prize in Chemistry, Peter Agre has focused his research on the role of aquaporins in malaria.
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Slides from the Lightning Talks presented at this year's JHMRI World Malaria Day Symposium can be downloaded from the conference page. Please attend again in 2022.
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MIAM is a research field station and training center in Zambia addressing transmission, diagnosis, drug evaluation and the treatment of malaria.
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In the News
- Science publishes study identifying First-Ever Anopheles Pheromone with Potential for Mosquito Population Control (Jacobs-Lorena lab)
- William Moss, MD, JHMRI Deputy Director, speaks with the BBC about how a one-size-fits-all COVID vaccine will not work everywhere in Africa.
- Geervani Daggupati receives Young Investigator Award First-Tier Mention at the ASTMH annual meeting (Srinivasan lab)
- Yuemei Dong, Maria L. Simões, and George Dimopoulos engineer mosquitoes that resist malaria parasites
- Diego Giraldo Sanchez in the McMeniman Lab wins Human Frontier Science Program Fellowship to study neuromodulatory networks controlling mosquito attraction to humans
- Toxoplasma is "like a bomb you have in the brain," says professor Isabelle Coppens in the Spring issue of the Johns Hopkins Public Health magazine
- Graduate Student Jordan Hoffman shares her as a Global Health Established Field Placement
- Nature publishes article on our field site Macha Research Trust in Zambia
- The National Health Research Authority of Zambia honors the Macha Research Trust field site with Outstanding Research Institution Award at the 8th Annual Zambia National Health Research Conference
- Young scientists organize, attend malaria conference at Johns Hopkins University in Rockville, Maryland November 2018 Hopkins Happenings (Trainees: Pringle, Nasir, Tauxe)
- Sequencing a malaria mosquito's motherline The JHU Hub (Norris)
- Chris Potter receives 2018 Johns Hopkins Catalyst Award
- George Dimopoulos receives the Shikani/El-Hibri Prize for Discovery & Innovation
- Mosquito Gut Bacteria May Offer Clues to Malaria Control The New York Times (Dimopoulos, Jacobs Lorena)
- The microbes in a mosquito’s gut may help fight malaria Science (Dimopoulos, Jacobs-Lorena)
- What Mosquitoes Smell, and Why We Should Care. WYPR (Potter)
- Hopkins gets $10 million federal grant to continue efforts to control, end malaria Baltimore Sun (Moss)
- Why is the Government Spying on Mosquitoes? New Republic (Norris)
- New Johns Hopkins Research may unlock how mosquitoes expereince human flavor Baltimore Sun (Potter)
- Fighting Malaria by Changing the Flavor of Humans Voice of America (Potter)
- Researchers identify fungus that makes mosquitoes more susceptible to malaria infection News-Medical.net (Dimopoulos)
- USAID awards Zika grant funding to three Johns Hopkins research teams Fox 45 News (Dimopoulos and McMeniman)
- Engineering Mosquitoes’ Genes to Resist Malaria. The New York Times. (Dimopoulos)
- New Concerns About Fighting Malaria. NPR The Diane Rehm Show. (Moss)
- Why a Vaccine that Works Only a Third of the Time is Still a Good Deal. NPR Goats and Soda. (Moss)
- Your Summertime Guide to Mosquitoes: Why They Like to Bite. The Washington Post. (Norris)
- Gains Being Made Against Malaria. Voice of America. (Moss)
- Malaria Eradication: Blocking Transmission to Mosquitoes. The Pharmaceutical Journal. (Dinglasan)
- A Conversation with Peter Agre (video recording). Neill, Ushma. The Journal of Clinical Investigation. (Agre)
- To beat malaria and dengue, vaccinate the mosquitoes.Science. (Dimopoulos)
Malaria afflicts 229 million people globally and kills approximately 409,000.*
The Johns Hopkins Malaria Research Institute’s state-of-the-art facility is the hub for a community of multidisciplinary researchers dedicated to treat, control and eradicate this deadly disease.
Focused on four major areas of research: Entomology, Parasitology, Epidemiology and Immunology, JHMRI boasts experts from around the globe, all working to prevent and cure malaria.
*World Health Organization, World Malaria Report 2020
Video: The War on Malaria - Johns Hopkins Malaria Research Institute Scientists Lead the Fight